StaffAndrea Vornoli


Informations



E-mail
vornoli@ibba.cnr.it

Phone
+39 0506212712

Office
Pisa

Research area
QUALY


ORCID: 0000-0003-1823-2865
Research Gate: Andrea Vornoli
Scopus Author ID: 56180609100
WoS Researcher ID: P-6509-2018
Linkedin: Andrea Vornoli
Google Scholar: Profile

Vornoli Andrea

Researcher

Education

2012-2016: PhD in Pharmacological and Toxicological Sciences, University of Bologna

2008-2010: Master’s degree in Biomolecular Sciences and Technologies, University of Pisa, 110/110 cum laude

2005-2008: Bachelor’s degree in Molecular Biological Sciences, University of Pisa, 110/110 cum laude

Professional experience

2022-Present: Permanent researcher at IBBA, CNR, Pisa

2019-2022: Fellowship at the University Hospital of Bologna Policlinico Sant’Orsola-Malpighi, and at the Cesare Maltoni Cancer Research Center of the Ramazzini Institute

2017-2018: Postdoc Fellowship at the National Institute of Environmental Health Science (NIEHS), NIH, North Carolina, USA

2016-2017: Fixed-term contract at the Cesare Maltoni Cancer Research Center of the Ramazzini Institute

2015: PhD stage abroad at Unidad de Hepatologia Experimental, Instituto de Investigacion Sanitaria La Fe, Valencia, Spain

2012-2016: Research grant at IBBA, CNR, Pisa.

2011-2012: Post-graduate stage at immunohematology laboratory of the Azienda Ospedaliero-Universitaria Pisana

2010: Master’s Degree Internship at the Department od Biochemistry of the University of Pisa

2008: Bachelor’s Degree Internship at IFC, CNR, Pisa

Research interests

  • Use of animal models (of hepatic steatosis, diabetes) for the evaluation of the anti-steatotic and hypoglycemic effects of nutraceuticals, through molecular biology, biochemical analyses and histopathological evaluation.
  • Evaluation of the effect of exogenous substances (natural or synthetic) in vivo (mouse and rat) on the enzymatic system of drug metabolism (P450, phase II, antioxidants), glucose, lipid, cholesterol, bile acid metabolisms and intracellular pathways through assays of enzymatic activity and gene and protein expression analyzes.
  • Evaluation of histopathological samples through immunohistochemical techniques and molecular biology analyzes.
  • Nutritional studies on the main and secondary bioactive components of foods, and evaluation of the antioxidant power of nutraceuticals
  • Characterization and treatment of cell lines for the evaluation of the protective / toxic capacities of environmental pollutants, natural substances and of agri-food interest.

 

Projects in progress

Projects completed

ALIFUN - Development of functional foods for the innovation of traditional Italian food products
Start date: 30/04/2021   End date: 30/09/2023

MUR

Pisa   Website

Vincenzo Longo

Project duration:
30/04/2021 - 30/09/2023
Financing body:
MUR
Project research leader:
Vincenzo Longo
Headquarters:
Pisa
Project website:
Website

ALIFUN - Development of functional foods for the innovation of traditional Italian food products


The main objective of the project is to develop various industrial-scale prototypes of functional foods using food matrices typical of Italian tradition. This objective will be pursued by characterizing the presence of naturally occurring or added bioactive components in the food and through the prototyping of novel foods relevant to the health sector of the agri-food industry.

The amount of funding received from the European Union for the Institute totals €70,592.67. IBBA’s role will involve evaluating the protective effect of a pasta enriched with artichoke flour (Cynara cardunculus scolymus) in response to steatosis induction. The pasta will be supplied by ISPA-CNR in Bari.

The aim of the experimental activity is to verify the pasta’s protective effects, including antioxidant, hypolipidemic, anti-inflammatory properties, and its impact on drug metabolism enzymes in rats treated with a hyperlipidic diet.

POSTER

Istituto

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