De Filippo Carlotta
Senior Researcher
Education
2018: National Scientific Qualification as Associate Professor of General Microbiology (05/I2, BIO19).
2003: Visiting Scientist at Bauer Center for Genomic Research, Harvard University (Cambridge, MA, USA)
2003: PhD in Pharmacology and Toxicology (University of Florence)
1999-2000: Visiting PhD student at Harvard School of Public Health (Boston, MA, USA)
1995: M.Sc. in Biology (University of Florence)
Professional experience
2020-Present: Senior Staff Researcher at CNR-IBBA, Pisa, Italy
2016-2020: Staff Researcher at CNR-IBBA, Pisa, Italy
2015-2016: Research fellow at CNR-IBIMET, Florence, Italy
2011-2015: Staff Researcher, Dep. Food Quality and Nutrition, Fond. E.Mach, San Michele all’Adige (TN), Italy
2006-2011: Research fellow in Nutrigenomics, Dep. of Preclinical and Clinical Pharmacology, University of Florence Italy
2003-2006: Post-doctoral fellow, Dep. of Preclinical and Clinical Pharmacology, University of Florence, Italy
Research interests
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Study of the structure, the gene content and the function of complex microbial communities (bacteria and fungi) that coexist and interact in the human and animal organism, by means of metagenomics (Next Generation Sequencing) and metabolomics. This approach integrates several multidisciplinary skills, including functional genomics, metagenomics, metabolomics and bioinformatics aimed at studying molecular determinants modulating the host’s immune response.
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Metagenomics’ application to the study of microbiota variability in African and Italian rural populations, to assess how regional diversity in the diet is associated with differences in the microbiome, and how these differences are endangered by the globalization of food. These studies contributed to the understanding of the combined role of diet and intestinal microbiota in the metabolism of molecules that are fundamental for intestinal health, such as short chain fatty acids (SCFAs).
