StaffSilvia Gianì


Informations



E-mail
giani@ibba.cnr.it

Phone
+39 0223699440

Office
Milano

Research area
BIOTEC, QUALY, BIOGEN


ORCID: 0000-0001-8740-1787
Google Scholar: Profile
Scopus Author ID: 7004436740
Linkedin: Silvia Granì
WoS Researcher ID: AAV-3716-2020

Gianì Silvia

Associate scientist

Education

1985: Postgraduate in General Pathology at Università Cattolica del Sacro Cuore- Rome, cum laude

1979: Doctoral Degree in Biological Sciences, University of Rome, cum laude

Professional experience

2021-Today: Associate to CNR – IBBA

1990-2021: Permanent researcher, III level at CNR IBBA

1988- 1989: Visiting Scientist q5 Department of Microbiology, North Carolina State University, Raleigh N.C., U.S.A (Lab Dr. K. Tatchell)

1988: Visiting Scientist at Laboratory of Molecular Virology, National Institute of Health NIH-NCI, Bethesda, Maryland, U.S.A. (Lab Dr. R. Dhar)

1987: Visiting Scientist at laboratory of Tumor Immunology and Biology of the National Institute of Health- National Cancer Institute, NIH Bethesda USA (Lab. dr. Schlom)

1984-1987: Research grant (professional training grant) – ex law 285- at the C.N.R. Center of Physiology of Muscular Work, then Institute of Advanced Biomedical Technologies (ITBA), works in command at the National Cancer Institute of Milan, in the laboratory of Experimental Oncology E (Dr. MIColnaghi), in collaboration with Prof. F Fazio of the Department of Nuclear Medicine and Cyclotron of the ITBA at the San Raffaele Hospital in Milan. 1982-1983: Postdoctoral position at Wistar Institute of Anatomy and Biology of Philadelpia USA (Lab dr. M. Trucco)

1981 -1990: Professional training allowance, ex law 285/1977 National Research Council, Rome

1982-1983: Post dottorato presso il Wistar Institute of Anatomy  and Biology di Philadelpia USA  (Lab dr. M. Trucco)

1981-1990: Assegno di formazione professionale, ex   legge 285/1977 Consiglio Nazionale delle Ricerche, Roma

Research interests

  • Study of the cytoskeleton of plant organisms, in particular of the microtubules that are investigated with cell biology, biochemistry and molecular biology approaches.
  • Study of the mechanisms of action of anti-mitotic compounds, used as plant growth inhibitors and characterization of the effect of some herbicides on the proliferation of Prototheca cells.
  • Study of the mechanisms that regulate the expression of the genes of the plant tubulin family, setting up, for the purpose, also experiments with transgenic plants.
  • Study of the introns of plants both as elements that contribute to the control of gene expression and as useful elements for traceability and the genetic certification of crops, products of plant origin and products intended for food consumption.
  • Development and validation of diagnostic tools for food traceability (TBP-Tubulin based Polymorphism).

Projects in progress

Genotyping of the Landolt Duckweed Collection
Start date: 01/08/2021   End date: 31/07/2024

Landolt Duckweed Collection

Milano
Laura Morello

Project duration:
01/08/2021 - 31/07/2024
Financing body:
Landolt Duckweed Collection
Project research leader:
Laura Morello
Headquarters:
Milano

Genotyping of the Landolt Duckweed Collection


The project is aimed at the genotyping, through plastid and nuclear molecular markers (TBP), of the whole collection of small aquatic macrophytes (Lemnaceae) known under the name of Landolt Duckweed Collection and currently managed by Dr Lammler in Zurich. This historical collection, the largest in Europe, includes about 500 clones of the 36 known duckweed species, coming from five continents. Accessions have been mostly characterized on a morphological basis, which may cause a high rate of misclassifications in some species, owing to the simplified structure of these tiny plants and the high similarity between some species.

Since long used as environmental bioindicators, duckweeds and renowned for their phytoremediation capacity. Due to their extraordinary fast growth, duckweeds are one of the most promising new crops, under intensive study for energy production and as a source of high quality proteins for animal and human nutrition, already under evaluation as a novel food by EFSA.

Results will be useful to:

  • ascertain the classification of all clones, many of which are under study in many laboratories worldwide
  • evaluating inter and intraspecific biodiversity
  • contribute to duckweed taxonomy
  • understanding duckweed evolution.

Projects completed

RABoLa - Sustainable strategies to reduce the use of antibiotics in dairy farming
Start date: 28/12/2018   End date: 27/06/2022

Regione Lombardia

Milano, Lodi   Website

Paola Cremonesi, Laura Morello

Project duration:
28/12/2018 - 27/06/2022
Financing body:
Regione Lombardia
Project research leader:
Paola Cremonesi, Laura Morello
Headquarters:
Milano, Lodi
Project website:
Website

RABoLa - Sustainable strategies to reduce the use of antibiotics in dairy farming


The project, which involves different departments of the University of Milan (DISAA, DIMEVET, VESPA), researchers from the CNR ISPA and CNR IBBA and the DIANA Department of the Catholic University of the Sacred Heart of Piacenza, aims the primary identification of operative practices for reducing the use of antibiotics in the dairy cow herds. During the study, operative protocols already preliminary tested (administration of Aloe arborescens, use of Lactococcus lactis subsp. cremoris in pre and post dipping, molecules to inhibit Prototheca spp) will be validated during the entire lactation cycle of the cows.

This project will allow breeders to take advantages of new nutraceutical strategies and alternatives to the use of antibiotics, to enhance the innate defences and reduce the incidence and severity of mastitis. The validation of an effective protocol for the selective drying of animals would lead to a reduction of the preventive use of antibiotics, in line with what is requested at European level.

BIO-MEMORY
Start date: 15/10/2021   End date: 15/02/2024

CNR

Milano, Lodi, Pisa, Roma
Flavia Pizzi, Aldo Ceriotti

Project duration:
15/10/2021 - 15/02/2024
Financing body:
CNR
Project research leader:
Flavia Pizzi, Aldo Ceriotti
Headquarters:
Milano, Lodi, Pisa, Roma

BIO-MEMORY


The project is organized in 3 main activities:

1) Implementation and updating of the BioGenRes network of biobanks, with a focus on nationally/internationally recognized collections of animal, plant or microorganism species samples (animal and plant germplasm banks, microbial strain libraries of pathogenic/toxigenic organisms, nematodes, soil and water microflora and microorganisms used in agro-industry and food (e.g. microbial starters for fermentations)).

2) Replication (rejuvenation) and expansion of material stored in collections. For plant and microbial collections: multiplication of accessions for which a small amount of material is available and rejuvenation of accessions whose seed viability data are below the expected standards (> 85%). For animal collections of zootechnical interest: collection and freezing of genetic material of local breeds to complete sampling carried out in previous projects or expansion of the number of species and breeds stored in cryobanks.

3) Biochemical, molecular, metabolic, functional and phenotypic characterization of the material conserved in the biobanks of the BioGenRes network, also in order to carry out association studies and to identify markers associated with traits linked to production and/or adaptation to biotic and abiotic stress factors.

sPATIALS3 - Improvement of agrifood productions and innovative technologies for a safer and more secure and sustainable nutrition
Start date: 01/02/2020   End date: 31/10/2022

Regione Lombardia

Milano, Lodi   Website

Francesca Sparvoli

Project duration:
01/02/2020 - 31/10/2022
Financing body:
Regione Lombardia
Project research leader:
Francesca Sparvoli
Headquarters:
Milano, Lodi
Project website:
Website

sPATIALS3 - Improvement of agrifood productions and innovative technologies for a safer and more secure and sustainable nutrition


sPATIALS3 is a technological and research hub involving 12 CNR Institutes belonging to 4 different Departments and 4 companies. Main objectives will be: obtainment of innovative food products improved for their nutritional and functional properties; provision and implementation of precision technologies to guarantee products quality, safety and traceability; development of innovative and eco-sustainable smart– and active-packaging to minimize and reuse wastes, where possible, and to increase food preservability; provision to consumers and producers of tools for results exploitation.

FNS-CLOUD: Food Nutrition and Security Cloud
Start date: 01/10/2019   End date: 30/09/2023

EU REA - Research Executive Agency

Milano   Website

Diego Breviario

Project duration:
01/10/2019 - 30/09/2023
Financing body:
EU REA - Research Executive Agency
Project research leader:
Diego Breviario
Headquarters:
Milano
Project website:
Website

FNS-CLOUD: Food Nutrition and Security Cloud


In this project it is planned to implement a search engine demonstrator tailored for scientific food data. Couple food data with data on metrological tools.
Search and integrate food data within the FNS-Cloud.
Gives to users an overview of available data and organise them in a really useful way for them.
Istituto

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